New methadone protocol aims to ease pain and cut opioid use in kids after heart surgery

NCT ID NCT06626035

Recruiting now Symptom relief Sponsor: Senthil Sadhasivam Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tests a methadone-based recovery plan to improve pain control and reduce opioid use in children after heart surgery. About 500 children aged 3 to 18 will be randomly assigned to either the new methadone plan or standard care. The goal is to see if the new approach lowers pain scores and the amount of opioids needed.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PEDIATRIC CARDIAC SURGERY

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center
NOT_YET_RECRUITING

Cincinnati, Ohio, 45229, United States
UCSF Benioff Children's Hospital
NOT_YET_RECRUITING

Oakland, California, 94618, United States
UPMC Children's Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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