New combo pill eases foot surgery pain in trial

NCT ID NCT05868122

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a fixed-dose combination of acetaminophen and naproxen sodium (two common pain relievers) against a placebo for managing pain after bunionectomy (foot surgery). 143 adults took multiple doses over 48 hours. The main goal was to measure pain reduction using a standard pain scale. Results showed the combination was more effective than placebo at reducing pain intensity.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Endeavor Clinical Trails

    San Antonio, Texas, 78240, United States

  • First Surgical Hospital

    Bellaire, Texas, 77401, United States

  • Lotus Clinical Research, LLC

    New Providence, New Jersey, 07974, United States

  • The Heights Hospital / Memorial Herman Village

    Houston, Texas, 77008, United States

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