New nerve block could ease pain for liver donors
NCT ID NCT07233096
First seen Nov 18, 2025 · Last updated Jun 23, 2026 · Updated 33 times
Summary
This study tests whether a special nerve block called the rectus-intercostal fascial plane (RIFP) block can reduce pain and the need for morphine in people who donate part of their liver. Sixty-four donors will be randomly assigned to get either the block plus standard pain medicine or standard pain medicine alone. The main goal is to see how much morphine they need in the first 24 hours after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
istinye University
RECRUITINGIstanbul, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine
What this could lead to
If it works, this could give liver donors better pain control with less morphine, helping them recover faster.
What could go wrong
This is a small, early-phase trial. The block may not reduce pain or morphine use significantly, and there are rare risks like infection or allergic reaction.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.