New study tests if two painkillers beat one for brace pain
NCT ID NCT04059172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a combination of ibuprofen and acetaminophen against ibuprofen alone or a placebo for pain after getting braces. 375 people scheduled for braces will take one of the three treatments for four days and rate their pain. The goal is to see if the combo offers better relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ibuprofen and acetaminophen
What this could lead to
If it works, this could point toward a better way to manage pain after getting braces.
What could go wrong
This is a very early phase trial, so results may not be conclusive. The combination might not work better than ibuprofen alone, or side effects could occur.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Colorado, School of Dental Medicine
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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