New study tests if two painkillers beat one for brace pain
NCT ID NCT04059172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a combination of ibuprofen and acetaminophen against ibuprofen alone or a placebo for pain after getting braces. 375 people scheduled for braces will take one of the three treatments for four days and rate their pain. The goal is to see if the combo offers better relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ibuprofen and acetaminophen
- What this could lead to
- If it works, this could point toward a better way to manage pain after getting braces.
- What could go wrong
- This is a very early phase trial, so results may not be conclusive. The combination might not work better than ibuprofen alone, or side effects could occur.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Colorado, School of Dental Medicine
RECRUITINGAurora, Colorado, 80045, United States
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