Spine surgery pain showdown: nerve block vs. IV cocktail

NCT ID NCT07455565

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pain management methods for people having elective lower back surgery. One group gets an ultrasound-guided nerve block (erector spinae plane block) with bupivacaine, while the other receives a combination of pain medicines through an IV. Researchers will use a special monitor that tracks heart rate changes to measure pain levels, along with standard pain scores. The goal is to find out which approach provides better pain relief after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine (nerve block) and a combination of paracetamol, morphine, dexamethasone, and ketamine (intravenous multimodal analgesia)

What this could lead to

If successful, this study could show which pain relief method works better after spine surgery, helping doctors improve patient comfort and reduce side effects.

What could go wrong

This is a small, early-stage study with only 100 participants. Results may not apply to all patients or surgeries, and both methods have known risks like nausea or allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Akdeniz University Faculty of Medicine Hospital

    RECRUITING

    Antalya, Antalya, 0707, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••