New pain block study aims to ease recovery after mastectomy

NCT ID NCT07650305

Recruiting now Symptom relief Sponsor: National Cancer Institute, Egypt Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two different nerve block techniques—bilevel erector spinae plane block and pecto-serratus block—to see which provides better pain relief after modified radical mastectomy in breast cancer patients. Sixty women will be enrolled and their painkiller use and pain scores will be tracked. The goal is to find a safer, more effective way to manage post-surgery pain and reduce reliance on opioids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nerve block (local anesthetic injection)
What this could lead to: If one block works better, it could mean less pain and less need for strong painkillers after mastectomy.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Nerve blocks carry risks like infection or bruising.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

National Cancer Institute - Cairo University
RECRUITING

Cairo, 11796, Egypt

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