Cheaper pain cocktail may rival exparel in kidney surgery trial
NCT ID NCT07092566
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This phase 3 trial tests whether a combination of four drugs (R.E.C.K) controls pain after robotic kidney surgery as well as the more expensive drug Exparel. About 170 adults having robotic partial or total kidney removal will be randomly assigned to receive one of the two injections during surgery. Researchers will track pain scores, painkiller use, and hospital stay length to see if the cheaper option is just as effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ropivacaine, epinephrine, clonidine, and ketorolac (R.E.C.K) or liposomal bupivacaine (Exparel)
What this could lead to
If R.E.C.K works as well as or better than the more expensive Exparel, it could provide a cheaper, effective option for managing pain after kidney surgery.
What could go wrong
This is a single-center trial with 170 people, so results may not apply to all hospitals or surgeries. Pain is subjective, and individual responses vary.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Levine Cancer
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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