New combo could ease back surgery pain without opioids
NCT ID NCT07573969
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine or ketamine to a standard numbing medicine (bupivacaine) can provide longer pain relief after lower back surgery. 72 adults undergoing lumbosacral surgery will receive one of three mixtures via a caudal block. The main goal is to see how long pain relief lasts before needing morphine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bupivacaine with either dexmedetomidine or ketamine
- What this could lead to
- If it works, this could point toward a better way to manage pain after back surgery, reducing the need for strong opioids.
- What could go wrong
- This is a small, early-stage trial (72 people) comparing two additives; results may not apply to all patients or surgeries. Both additives have known side effects like nausea or blood pressure changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams University hospitals
RECRUITINGCairo, Egypt
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