New combo could ease back surgery pain without opioids
NCT ID NCT07573969
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine or ketamine to a standard numbing medicine (bupivacaine) can provide longer pain relief after lower back surgery. 72 adults undergoing lumbosacral surgery will receive one of three mixtures via a caudal block. The main goal is to see how long pain relief lasts before needing morphine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine with either dexmedetomidine or ketamine
What this could lead to
If it works, this could point toward a better way to manage pain after back surgery, reducing the need for strong opioids.
What could go wrong
This is a small, early-stage trial (72 people) comparing two additives; results may not apply to all patients or surgeries. Both additives have known side effects like nausea or blood pressure changes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ain Shams University hospitals
RECRUITINGCairo, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••