New study aims to cut opioid use in kidney donors
NCT ID NCT06764667
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to manage pain in 60 people donating a kidney through keyhole surgery. One group received spinal anesthesia with added morphine, while the other got a nerve block near the lower back. The goal was to see which method reduces the need for opioid painkillers and improves recovery. The trial has already been completed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Bupivacaine and Morphine
- What this could lead to
- If successful, this could point to a better way to manage pain after kidney donation, reducing the need for strong opioids.
- What could go wrong
- This is a small, completed study with 60 participants, so results may not apply to all patients. The two methods may show no significant difference.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
-
Jan 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-65 years undergoing laparoscopic donor nephrectomy * Patients with BMI ≤ 35 kg/m2 * Patients with American Society of Anesthesiology (ASA) physical status 1-2 * Patients who are willing to participate in this study Exclusion Criteria: * Cardiovascular disease (uncontrolled stage 2 hypertension, heart failure, arrhytmia) * Recent onset cerebrovascular diseasae of \< 3 months * Infection on spinal site * Coagulopathy * Elevated intracranial pressure * Severe renal or liver dysfunction * Valvular heart disease or atrioventricular block
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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RSUP dr. Cipto Mangunkusumo
Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia
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