New pain combo may cut opioid use after Kids' chest surgery

NCT ID NCT07290582

First seen Jan 05, 2026 · Last updated Jun 20, 2026 · Updated 30 times

Summary

This study looks at 50 children having the Nuss procedure for pectus excavatum (sunken chest). It compares standard pain control (freezing the nerves between the ribs) to that method plus freezing a nerve near the diaphragm. Researchers want to see if the combo reduces pain scores and the need for extra pain medicine, and if it helps kids get out of bed and go home sooner.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PECTUS EXCAVATUM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sc Ricerca Clinica, Sviluppo E Innovazione

    RECRUITING

    Bergamo, BG, 24100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

phrenic nerve infiltration with cryoanalgesia

What this could lead to

If successful, this could lead to a better pain management strategy that reduces opioid use and speeds up recovery after pectus excavatum surgery.

What could go wrong

This is a small, observational study with only 50 participants, so results may not apply to all patients. The combined technique may not provide significant benefit over the standard approach.

Conditions

The condition(s) this trial relates to.

pectus excavatum respiratory paralysis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.