Absorbable chest scaffold aims to reshape sunken sternum without metal

NCT ID NCT05451108

First seen Jul 10, 2026 ยท Last updated Jul 10, 2026

Summary

This trial tests a new approach for pectus excavatum, a condition where the chest appears sunken. The method uses a custom 3D-printed scaffold made of absorbable material, similar to dissolvable stitches, combined with the patient's own fat cells to fill and reshape the chest. The scaffold supports tissue growth and then dissolves over time, leaving natural tissue behind. The study involves 7 adults aged 18 to 55 and focuses on safety and how well the fat and scaffold integrate.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
3D-printed absorbable polycaprolactone scaffold with autologous fat grafting
What this could lead to
If it works, this could offer a less invasive way to correct pectus excavatum using the body's own healing, avoiding permanent metal implants.
What could go wrong
This is a very small early safety trial with only 7 participants, so results may not apply broadly. Risks include infection, poor fat retention, or scaffold-related complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Princess Alexandra Hospital - Wooloongabba

    Brisbane, Queensland, 4102, Australia

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