Younger women may feel more pain from chemo support drug, study suggests

NCT ID NCT04174742

Ongoing Knowledge-focused Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study is looking at whether younger women (45 and under) feel more pain from a drug called pegfilgrastim, which is given during chemotherapy for breast cancer, compared to older women. About 115 women will report their pain levels and have their blood counts checked. The goal is to better understand who might need extra pain management, not to change cancer treatment itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pegfilgrastim (or a biosimilar version)
What this could lead to: If it works, this could help doctors better manage pain from this drug in younger breast cancer patients.
What could go wrong: This is a small, observational study that only measures pain and blood counts—it won't test a new treatment or change cancer therapy directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST BREAST CANCER

Contacts and locations

Locations

Levine Cancer Institute

Charlotte, North Carolina, 28204, United States
Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, 27157, United States

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