Could Opioid-Free pain relief be safer for kids with sleep apnea?

NCT ID NCT07435493

Not yet recruiting Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares standard fentanyl pain medicine to an opioid-free mix of acetaminophen, ibuprofen, ketamine, and dexamethasone in 64 children aged 5-10 with mild to moderate sleep apnea undergoing tonsil surgery. The goal is to see if the opioid-free option controls pain just as well but with fewer breathing problems and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fentanyl, acetaminophen, ibuprofen, ketamine, dexamethasone
What this could lead to: If successful, this could show that a combination of non-opioid drugs can control pain safely in children with sleep apnea, reducing breathing complications.
What could go wrong: This is a small, early-stage trial with only 64 children, so results may not apply to all. The opioid-free approach might not control pain as well as fentanyl.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADENOTONSILLECTOMY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOTONSILLECTOMY FENTANYL OBSTRUCTIVE SLEEP APNEA (OSA) OPIOID

Contacts and locations

Locations

Ain shams university

Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.