Knee replacement patients may use fewer opioids with new pain block
NCT ID NCT03747146
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to manage pain after total knee replacement: a single-shot nerve block versus a continuous nerve block using a small catheter. About 94 adults having knee surgery will be randomly assigned to one method. The goal is to see which approach reduces opioid painkiller use and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
continuous adductor canal catheter with saline
What this could lead to
If successful, this could show that a continuous nerve block provides better pain relief and reduces opioid use after knee replacement surgery.
What could go wrong
This is a small, early-stage study with only 94 participants, so results may not apply to everyone. The intervention is a device and saline, not a new drug, so the impact is limited to pain management.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10023, United States
Contact