Which painkiller works best after major head and neck surgery?
NCT ID NCT06784999
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two pain medicines, sufentanil and methadone, given during head and neck reconstruction surgery. About 128 adults will be randomly assigned to receive one of the drugs. Researchers will track pain levels and how much extra pain medicine is needed after surgery to see which drug works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sufentanil and methadone
- What this could lead to
- If this trial succeeds, it could show which pain medicine works better for patients after head and neck reconstruction, leading to improved pain management and recovery.
- What could go wrong
- This is a small, early-phase study (128 participants) comparing two existing drugs, so results may not apply to all patients. Pain relief varies individually, and both drugs have side effects like nausea or drowsiness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FREE FLAP RECONSTRUCTION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.