Can cold also turn off pain? new study investigates
NCT ID NCT07395869
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether a phenomenon called 'offset analgesia'—where pain briefly increases then drops sharply—can be triggered by cold temperatures, not just heat. Researchers will also map where pain and itch receptors are located on the body. Thirty healthy adults aged 18-60 will participate, rating their sensations on a scale. The goal is to better understand how pain and itch work, which could inform future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could improve understanding of how the body processes pain and itch, potentially guiding future pain treatments.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. Results may not apply to real-world pain conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Center for Neuroplasticity and Pain Faculty of Medicine, Aalborg University Selma Lagerløfs Vej 249 9260 Gistrup, Denmark
Aalborg, Aalborg, 9620, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••