New procedure shows promise for treating pulmonary hypertension
NCT ID NCT03282266
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a procedure called pulmonary artery denervation (PADN) for people with pulmonary arterial hypertension (PAH), a condition where blood pressure in the lungs is dangerously high. 128 adults received either the real procedure or a sham (fake) procedure. The goal was to see if PADN could improve how far they could walk in 6 minutes and lower their lung blood pressure. Results showed that those who got the real procedure walked farther and had lower blood pressure in their lungs after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pulmonary artery denervation (PADN) procedure
What this could lead to
If successful, PADN could offer a new treatment option for people with pulmonary arterial hypertension, potentially improving their ability to exercise and reducing strain on the heart.
What could go wrong
This is a single, completed trial with 128 participants. The procedure is invasive and carries risks like chest pain. More studies are needed to confirm long-term safety and effectiveness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Nanjing First Hospital
Nanjing, Jiangsu, 210006, China