New combo chemo regimen shows promise in early cancer trial

This early-phase study tested a combination of two chemotherapy drugs—weekly paclitaxel given through a vein and daily oral cyclophosphamide—in 28 adults with advanced cancer who had no other treatment options. The goal was to find the safest dose of paclitaxel when used with a fixed dose of cyclophosphamide. Researchers monitored side effects and checked if tumors shrank or stayed stable after two treatment cycles.