Can a common chemo drug be matched to tumor genetics?
NCT ID NCT03096418
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study gives paclitaxel (Taxol) to 50 women with breast cancer before surgery to see if tumors with high chromosomal instability respond better. Researchers will measure tumor shrinkage and drug levels in the tumor. The goal is to find biomarkers that predict who benefits most from this chemotherapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Paclitaxel (Taxol)
What this could lead to
If successful, this could help doctors predict which breast cancer patients will benefit most from paclitaxel before surgery, personalizing treatment.
What could go wrong
This is a small, early-phase study focused on biomarkers, not a treatment trial. Results may not change practice or apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Iowa Health Care/Holden Comprehensive Cancer Center
RECRUITINGIowa City, Iowa, 52242, United States
Contact
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University of Wisconsin Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53792, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••