Can a 'Love Hormone' spray tame Prader-Willi symptoms?
NCT ID NCT02804373
First seen Dec 05, 2025 · Last updated Jun 23, 2026 · Updated 24 times
Summary
This study tested whether oxytocin nasal spray, sometimes called the 'love hormone,' can improve behavior and eating problems in adults with Prader-Willi syndrome. Fifty participants received either oxytocin or a placebo daily or every three days for 28 days. Researchers measured changes in behavior, eating habits, and brain activity using scans.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre de référence Prader-Willi - Hôpital Purpan
Toulouse, 31059, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxytocin nasal spray
What this could lead to
If it works, this could offer a new way to ease behavioral and eating problems in Prader-Willi syndrome, improving social function and quality of life.
What could go wrong
This is a small, completed Phase 2/3 trial. Results may not be strong enough to confirm benefit, and oxytocin may not work for everyone or could have side effects like nasal irritation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.