Can pressurized oxygen help heal infected broken bones?
NCT ID NCT07535164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to standard surgery and antibiotics is feasible for treating infected leg fractures. Fifty adults with confirmed or suspected infection will be randomly assigned to receive either standard care alone or standard care plus hyperbaric oxygen. The main goal is to see if a larger trial is possible, not yet to prove the treatment works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperbaric oxygen therapy (breathing pure oxygen at high pressure)
- What this could lead to
- If successful, this could pave the way for a larger trial that may show hyperbaric oxygen helps control infections in broken bones.
- What could go wrong
- This is a small pilot study (50 people) testing feasibility, not effectiveness. It is early-stage and may not lead to a proven treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FRACTURE RELATED INFECTION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Amsterdam UMC
Amsterdam, North Holland, 1105AZ, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.