Mini muscle sensor could unlock mitochondrial disease diagnosis

NCT ID NCT06819683

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a small device called a nanosensor that measures oxygen levels in muscle tissue. The goal is to see if it can accurately assess mitochondrial function in people with mitochondrial myopathy compared to healthy volunteers. If it works, this sensor could become a new tool to diagnose and monitor these diseases, which currently lack reliable biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxygen nanosensor device
What this could lead to
If successful, this nanosensor could provide a reliable way to diagnose and track mitochondrial muscle diseases, helping future treatment studies.
What could go wrong
This is a small, early-phase device study in 96 people. The nanosensor has never been tested in humans, so it may not work as expected or could cause discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • The Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

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