Oxygen dosing during surgery may reduce lung complications

NCT ID NCT06013098

First seen Mar 24, 2026 · Last updated Jun 23, 2026 · Updated 13 times

Summary

This study looked at whether using different oxygen concentrations during and after esophageal cancer surgery could lower the risk of lung collapse (atelectasis). 65 patients were randomly assigned to receive either 30% or 60% oxygen during two-lung ventilation. The main goal was to see how often lung collapse occurred after surgery, measured by CT scan. The results could help guide oxygen use in the operating room.

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Contacts and locations

Locations

  • the First Hospital of China Medical University

    Shenyang, Liaoning, 110001, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxygen

What this could lead to

If successful, this could help doctors choose the best oxygen levels during surgery to reduce lung problems after esophageal cancer removal.

What could go wrong

This is a small, completed Phase 4 trial with only 65 participants. Results may not apply to all patients or surgeries, and the benefit may be small.

Conditions

The condition(s) this trial relates to.

esophageal cancer Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.