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Can extra oxygen during rehab change how COPD patients breathe?

NCT ID NCT07107828

Symptom relief Sponsor: Eastern Switzerland University of Applied Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers are studying how a three-week inpatient pulmonary rehabilitation program affects breathing in people with COPD whose blood oxygen drops during exercise. Participants train while breathing normal air, air that mimics moderate altitude, or extra oxygen. A wearable sensor records their breathing before and after the program and around walking and cycling tests. The goal is to see whether supplemental oxygen during training changes breathing patterns and exercise endurance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supplemental oxygen during exercise training
What this could lead to
If supplemental oxygen during rehab helps, it could give doctors a clearer reason to prescribe it for COPD patients whose oxygen drops only during exercise. It could also show whether a wearable breathing sensor is useful for tracking rehab progress.
What could go wrong
This is a small study of 52 people over three weeks, so any breathing changes may be too slight or too short-lived to matter. Supplemental oxygen can cause dryness or nosebleeds, and the findings may not apply to COPD patients with different oxygen levels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Jul 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * aged ≥ 18 years * stable condition \> 3 weeks (e.g. no exacerbations) * resting SpO2 ≥ 88% and exercise induced hypoxemia defined by a fall in SpO2 by ≥ 4% and/or below 90% during a 6-minute walk test (6MWT) * informed consent as documented by signature. Exclusion Criteria: * Severe daytime resting hypoxemia (SpO2 \< 88%) * long-term oxygen therapy * unstable condition requiring adaptation of pharmacologic and other treatment modalities or requirement of intensive care or relevant severe concomitant disease * inability to follow the procedures of the study, e.g. due to language problems psychological disorders, neurological or orthopedic problems with walking disability or inability to ride a bicycle * women who are pregnant or breast feeding * enrolment in another clinical trial with active treatment.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Motor Activity Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD (chronic obstructive pulmonary disease)

Contacts and locations

Locations

  • National center for cardiology and internal medicine

    Bishkek, Kyrgyzstan

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