Myeloma drugs tested for home use: could cut hospital stays

NCT ID NCT05972135

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether two drugs, teclistamab and talquetamab, can be given safely in an outpatient setting for people with multiple myeloma. The study will enroll 100 participants who have already tried other treatments. The main goal is to see how often side effects like cytokine release syndrome (CRS) occur when preventive medicines are used, with the hope of making treatment more convenient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Teclistamab or Talquetamab (drugs given as shots under the skin)

What this could lead to

If successful, this could allow multiple myeloma patients to receive these powerful drugs safely as outpatients, reducing time in the hospital.

What could go wrong

This is a small, early-phase study (100 people) focused on safety and side effects, not yet on cure. Side effects like cytokine release syndrome (CRS) are still a risk, even with preventive medicines.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cytokine release syndrome plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arizona Oncology Associates

    RECRUITING

    Tucson, Arizona, 85711, United States

  • Blue Ridge Cancer Center

    RECRUITING

    Roanoke, Virginia, 24014, United States

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Florida Cancer Specialists

    WITHDRAWN

    Lake Mary, Florida, 32746, United States

  • Maryland Oncology Hematology

    RECRUITING

    Columbia, Maryland, 21044, United States

  • Medical Oncology Hematology Consultants

    RECRUITING

    Newark, Delaware, 19713, United States

  • Minnesota Oncology Hematology

    RECRUITING

    Minneapolis, Minnesota, 55404, United States

  • Oncology Associates of Oregon

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Oncology Hematology Care

    RECRUITING

    Cincinnati, Ohio, 45242, United States

  • Rocky Mountain Cancer Center

    RECRUITING

    Denver, Colorado, 80218, United States

  • Texas Oncology

    RECRUITING

    Austin, Texas, 78705, United States

  • Texas Oncology - Northeast Texas

    RECRUITING

    Tyler, Texas, 75702, United States

  • Texas Oncology - San Antonio

    RECRUITING

    San Antonio, Texas, 78240, United States

  • TriStar Bone Marrow Transplant

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Vanderbilt- Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Virginia Oncology Associates

    RECRUITING

    Elizabeth City, North Carolina, 27909, United States