New combo therapy shows promise for lung cancer patients with brain tumors

NCT ID NCT07491211

First seen Mar 26, 2026 · Last updated May 06, 2026 · Updated 4 times

Summary

This study looks at 300 adults with a specific type of advanced lung cancer (EGFR mutation) that has spread to the brain and causes symptoms. Patients received a targeted pill (osimertinib) plus focused radiation to the brain. The goal is to see if this combination helps control the cancer longer and improves survival. This is a real-world study using medical records from multiple hospitals.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, China, 200032, China

  • Shanghai Jiao Tong University Affiliated Chest Hospital

    Shanghai, China

  • Wuhan Tongji Hospital

    Wuhan, Hubei, China

Conditions

Explore the condition pages connected to this study.