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Which orthodontic wire hurts teeth roots least? a 3D showdown

NCT ID NCT07688655

Knowledge-focused Sponsor: Damascus University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study compares three different sequences of archwires used in braces to see which one causes the least damage to tooth roots and the bone around them. Researchers used 3D scans to measure root volume and bone height before and after treatment in 53 people aged 16–25 with moderate crowding. The goal is to help orthodontists choose a wire sequence that straightens teeth effectively while minimizing side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one archwire sequence clearly causes less root resorption and bone loss, it could become the preferred choice for safer orthodontic treatment.
What could go wrong
This is a small, single-center study with 53 participants, so results may not apply to all patients. The findings are observational and do not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

53 people

The number who actually took part.

Started

Mar 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 16 and 25 years * Presence of a complete permanent dentition * Moderate crowding ranging from 4 to 6 mm, according to Little's Irregularity Index (Little, 1975) * Indication for non-extraction orthodontic treatment * Normal or slightly retroclined incisors, as evaluated radiographically and on study models * Good oral health status * Periodontally healthy supporting tissues Exclusion Criteria: * Patients with severe skeletal discrepancies * Patients with craniofacial anomalies * Presence of impacted or supernumerary teeth * History of previous orthodontic treatment * Presence of systemic conditions or use of medications known to influence tooth movement * Pregnant women * Patients for whom the follow-up (T1) records were not obtained within the permitted 35-day window

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Conditions

The condition(s) this trial relates to.

Malocclusion malocclusion due to protuberant upper front teeth malposition of teeth with or without hypodontia/oligodontia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Malocclusion of anterior teeth Malocclusion; displaced teeth

Contacts and locations

Locations

  • Department of Orthodontics, Faculty of Dentistry, University of Damascus

    Damascus, Rif-dimashq Governorate, DM20AM19, Syria

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