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Mouthwash showdown: can hydrogen peroxide rinse beat gum disease?

NCT ID NCT07270705

Recruiting now Symptom relief Sponsor: ENIKAM d.o.o. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a hydrogen peroxide mouth rinse called OROXID can help treat gingivitis, a common gum inflammation. About 90 adults with mild gum disease will use the rinse twice daily for 4 weeks, alongside regular brushing. Researchers will measure changes in gum inflammation, plaque, and bleeding to see if it works better than brushing alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hydrogen peroxide mouth rinse (OROXID)
What this could lead to
If it works, this could provide a simple, over-the-counter option to help manage gingivitis and prevent it from worsening.
What could go wrong
This is a small, early-stage trial with only 90 people. Results may not apply to everyone, and hydrogen peroxide can sometimes irritate gums or cause sensitivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GINGIVITIS

Contacts and locations

Locations

  • Klinika Križaj Ljubljana

    RECRUITING

    Ljubljana, 1000, Slovenia

  • Ustna medicina d.o.o.

    RECRUITING

    Ljubljana, 1000, Slovenia

    Contact Email: •••••@•••••

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