Mini-Guts grown from patient biopsies to test new therapies

NCT ID NCT05425901

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 21 times

Summary

This study took small tissue samples from 16 people with and without inflammatory bowel disease (IBD) during routine colonoscopies. Researchers grew these samples into mini-organs called organoids in the lab. The goal was to see if they could reliably create these organoids and then use them to test how radiation and potential treatments affect the gut. This is a first step toward developing better therapies for IBD and radiation injury.

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Contacts and locations

Locations

  • Groupe Hospitalier Ambroise Paré Hartmann

    Neuilly-sur-Seine, Hauts-de-Seine, 92200, France

Conditions

Explore the condition pages connected to this study.