Lab-Grown tumor clones could pick best drugs for liver cancer patients

NCT ID NCT07363356

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether growing a patient's tumor cells in the lab (as organoids) can help doctors choose the most effective drugs after liver cancer surgery. 56 adults with high-risk features will have their tumor tested against several approved drugs. The goal is to see if this personalized approach improves how long patients stay cancer-free compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Organoid drug sensitivity testing to guide choice of Apatinib, Atezolizumab+Bevacizumab, Donafenib+Toripalimab, Sintilimab, or FOLFOX

What this could lead to

If successful, this approach could personalize cancer treatment after liver surgery, potentially reducing the chance of the cancer coming back.

What could go wrong

This is a small, early-phase trial (56 people) at one hospital. The organoid test may fail or not accurately predict which drug works best, and some drugs have serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEPATOCELLULAR CARCINOMA RESECTABLE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the Third Affiliated Hospital of Naval Medical University, Shanghai, Shanghai 200433/201805

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••