Hormone pill tested for prostate troubles – but trial halted early

NCT ID NCT00651807

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tested a hormone drug called etonogestrel (Org 3236) in 16 men with moderate to severe urinary symptoms from an enlarged prostate. The goal was to see if the drug could shrink the prostate, improve urine flow, and boost quality of life compared to a placebo. However, the study was terminated early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
etonogestrel (a hormone drug)
What this could lead to
If it works, this could point toward a new hormone-based treatment for enlarged prostate symptoms.
What could go wrong
This was a very small, early-phase trial that was terminated, so results are limited. The drug may not prove effective or safe in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Médico Especializado

    Buenos Aires, Hidalgo, 1405, Argentina

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