New daily pill shows promise in keeping lost weight off for good

NCT ID NCT06584916

First seen Jan 07, 2026 · Last updated May 15, 2026 · Updated 16 times

Summary

This study tested a once-daily pill called orforglipron to see if it helps people with obesity or overweight maintain weight loss they achieved in a previous study. 376 adults who completed the earlier weight-loss program took either the pill or a placebo. The goal was to measure how well the pill prevented weight regain over time.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research, LLC

    Norman, Oklahoma, 73069, United States

  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

    Troy, Michigan, 48098, United States

  • Biopharma Informatic, LLC

    Houston, Texas, 77043, United States

  • Cahaba Research

    Birmingham, Alabama, 35242, United States

  • Cahaba Research - Pelham

    Pelham, Alabama, 35124, United States

  • Encompass Clinical Research

    Spring Valley, California, 91978, United States

  • Iowa Diabetes and Endocrinology Research Center

    West Des Moines, Iowa, 50265, United States

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Lillestol Research

    Fargo, North Dakota, 58104, United States

  • New Horizon Research Center

    Miami, Florida, 33165, United States

  • North Texas Endocrine Center

    Dallas, Texas, 75231, United States

  • Palm Research Center Sunset

    Las Vegas, Nevada, 89148, United States

  • Palm Research Center Tenaya

    Las Vegas, Nevada, 89128, United States

  • PharmQuest Life Sciences, LLC

    Greensboro, North Carolina, 27408, United States

  • PlanIt Research, PLLC

    Houston, Texas, 77079, United States

  • Prime Health and Wellness/SKYCRNG

    Fayette, Mississippi, 39069, United States

  • Puerto Rico Medical Research

    Ponce, 00717, Puerto Rico

  • Rocky Mountain Clinical Research

    Idaho Falls, Idaho, 83404, United States

  • Rophe Adult and Pediatric Medicine/SKYCRNG

    Union City, Georgia, 30291, United States

  • Southern California Dermatology, Inc.

    Santa Ana, California, 92701, United States

  • Southern Endocrinology Associates

    Mesquite, Texas, 75149, United States

  • StudyMetrix Research

    City of Saint Peters, Missouri, 63303, United States

  • The University of Texas Health Science Center at Houston

    Bellaire, Texas, 77401, United States

  • Tribe Clinical Research, LLC

    Greenville, South Carolina, 29607, United States

  • University Clinical Investigators, Inc.

    Tustin, California, 92780, United States

  • Velocity Clinical Research, Dallas

    Dallas, Texas, 75230, United States

  • WR-Clinsearch, LLC

    Chattanooga, Tennessee, 37421, United States

  • Weill Cornell Medical College

    New York, New York, 10021, United States

  • Wellness clinical Research Vega Baja

    Vega Baja, 00694, Puerto Rico

Conditions

Explore the condition pages connected to this study.