Engineered stem cell graft aims to improve transplant success in blood cancers
NCT ID NCT03802695
First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 31 times
Summary
This early-phase study tests a new way to prepare donor stem cells (called Orca-Q) for transplant in people with certain blood cancers like leukemia. The goal is to see if this engineered graft is safe and helps the body accept the new cells without serious side effects. About 300 participants will receive the specially processed donor cells and be monitored for complications like graft failure or graft-versus-host disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope
RECRUITINGDuarte, California, 91010, United States
Contact
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Emory University
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30322, United States
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Froedtert Memorial Lutheran Hospital
WITHDRAWNMilwaukee, Wisconsin, 53226, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
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Ohio State University
ACTIVE_NOT_RECRUITINGColumbus, Ohio, 43210, United States
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Stanford Health Care
RECRUITINGStanford, California, 94305, United States
Contact
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The University of Kansas Hospital
WITHDRAWNKansas City, Kansas, 66160, United States
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UC Davis
RECRUITINGSacramento, California, 95817, United States
Contact
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University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77054, United States
Contact
Conditions
Explore the condition pages connected to this study.