Engineered donor cells aim to make stem cell transplants safer for blood cancer patients
NCT ID NCT03802695
First seen Oct 31, 2025 · Last updated Jun 17, 2026 · Updated 37 times
Summary
This study tests a new way to prepare donor stem cells (called Orca-Q) for people with blood cancers like leukemia or MDS who need a transplant. The goal is to see if this engineered graft is safe and helps the body accept the new cells with fewer complications. About 300 participants will receive the treatment and be monitored for side effects and how well the new cells take hold.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope
RECRUITINGDuarte, California, 91010, United States
Contact
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Emory University
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30322, United States
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
Contact
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Froedtert Memorial Lutheran Hospital
WITHDRAWNMilwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
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Ohio State University
ACTIVE_NOT_RECRUITINGColumbus, Ohio, 43210, United States
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Stanford Health Care
RECRUITINGStanford, California, 94305, United States
Contact
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The University of Kansas Hospital
WITHDRAWNKansas City, Kansas, 66160, United States
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UC Davis
RECRUITINGSacramento, California, 95817, United States
Contact
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University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77054, United States
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.