Orange you glad you ate that? study tests fruit against fatty liver

NCT ID NCT05558592

Completed Disease control Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether eating 400 grams of fresh oranges daily for a month could improve metabolism in 60 adults with metabolic-associated fatty liver disease (MAFLD). Participants either ate oranges or other fruits. Researchers measured changes in liver fat and blood fats. The goal was to see if oranges could help control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oranges (Navelina variety)
What this could lead to: If it works, this could point toward a simple dietary addition to help manage fatty liver disease and reduce metabolic risk.
What could go wrong: This is a small, completed study with only 60 participants. The results may not apply to everyone, and dietary changes alone may not be enough for significant improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic disease metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FATTY LIVER, NONALCOHOLIC METABOLIC DISEASE

Contacts and locations

Locations

IRCCS Saverio de Bellis

Castellana Grotte, BARI, 70013, Italy

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