New oral therapy cycle shows promise for tough prostate cancer

NCT ID NCT05081193

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tested a new way to treat men with advanced prostate cancer that no longer responds to standard hormone therapy. Fifteen men took high-dose oral testosterone for one week, then no treatment for one week, repeating for three months. If the cancer worsened, they switched to enzalutamide. The goal was to see if this approach could control the cancer and delay progression.

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Contacts and locations

Locations

  • Allegheny Health Network

    Pittsburgh, Pennsylvania, 15212, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.