Daily pill helps shed pounds in obesity trial

NCT ID NCT05564117

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tested a daily 25 mg semaglutide tablet in 307 adults with overweight or obesity to see if it helps with weight loss. Participants took the pill or a placebo for 64 weeks, followed by 7 weeks of follow-up. The main goals were to measure the percentage of weight lost and how many people lost at least 5% of their body weight. This is a disease control approach, as ongoing management may be needed.

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Contacts and locations

Locations

  • Accellacare

    Wilmington, North Carolina, 28401, United States

  • Beata Miklaszewicz&Dariusz Dabrowski "CARDIAMED" s.j.

    Legnica, Lower Silesian Voivodeship, 59-220, Poland

  • Centrum Zdrowia Metabolicznego

    Poznan, Wielkopolskie Voivodeship, 60-589, Poland

  • Diabetologische Gemeinschaftspraxis Dr. Staudenmeyer und Dr. Schiwietz

    Lingen, 49808, Germany

  • ETG Lublin

    Lublin, Lublin Voivodeship, 20-412, Poland

  • ETG Siedlce

    Siedlce, Masovian Voivodeship, 08-110, Poland

  • ETG Warszawa Sp. z o.o.

    Warsaw, Masovian Voivodeship, 02-677, Poland

  • East West Medical Research Institute_Honolulu

    Honolulu, Hawaii, 96814, United States

  • FDRC

    Costa Mesa, California, 92627, United States

  • G.A. Research Associates Ltd.

    Moncton, New Brunswick, E1G 1A7, Canada

  • Gabinet Leczenia Otylosci i Chorob Dietozaleznych

    Bialystok, Podlaskie Voivodeship, 15-281, Poland

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • MZM Praxis Drs. Erlinger

    Stuttgart, 70378, Germany

  • MedicalCenter am Clemenshospital - Schwerpunktpraxis für Diabetologie und Ernährungsmedizin

    Münster, 48153, Germany

  • Praxis Dr. med. Wenzl-Bauer

    Rehlingen-Siersburg, 66780, Germany

  • Praxis für Prävention und Therapie, Drs Jacob

    Villingen-Schwenningen, 78048, Germany

  • RED-Institut für medizinische Forschung und Fortbildung GmbH

    Oldenburg in Holstein, 23758, Germany

  • Selma Medical Associates

    Winchester, Virginia, 22601, United States

  • UT Southwestern Med Cntr

    Dallas, Texas, 75390-9302, United States

  • Univsty Of AL At Birmingham

    Birmingham, Alabama, 35294, United States

  • Washington Cntr Weight Mgmt

    Arlington, Virginia, 22206, United States

  • Wharton Med Clin Trials

    Hamilton, Ontario, L8L 5G8, Canada

  • Zentrum für klinische Studien Allgäu Oberschwaben

    Wangen, 88239, Germany

Conditions

Explore the condition pages connected to this study.