New pill targets 'MYC' cancer genes in advanced tumors

NCT ID NCT05546268

Summary

This early-phase study is testing an experimental oral medication called MRT-2359 in people with advanced cancers that have run out of standard treatment options. The trial focuses on several types of solid tumors and lymphoma, particularly those driven by specific genes called L-MYC or N-MYC. The main goals are to find a safe dose and see if the drug shows early signs of helping to control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Columbia University Irving Medical Centre

    New York, New York, 10032, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98109, United States

  • Henry Ford Cancer Institute

    Detroit, Michigan, 48202, United States

  • Honor Health Research Institute

    Scottsdale, Arizona, 85258, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030-4009, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75251, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • South Texas Accelerated Research Therapeutics (START)

    San Antonio, Texas, 78229, United States

  • South Texas Accelerated Research Therapeutics (START) Midwest

    Grand Rapids, Michigan, 49546, United States

  • South Texas Accelerated Research Therapeutics (START) Mountain Region

    West Valley City, Utah, 84119, United States

  • University of California San Diego

    San Diego, California, 92037, United States

  • University of Kansas Cancer Center

    Lawrence, Kansas, 66044, United States

  • Virginia Cancer Specialists Research Institute

    Fairfax, Virginia, 22031, United States

  • Washington University

    St Louis, Missouri, 63110, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.