Mint lozenge and water additive tested for microbiome impact in 595-Person study
NCT ID NCT07451782
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study enrolled 595 adults aged 18 to 80 to see how two marketed oral hygiene products—a dissolvable lozenge and a water additive—affect the bacteria, fungi, and viruses living in the mouth. Participants used the products daily for 60 days, and researchers analyzed saliva and oral swabs for changes in microbes, metabolites, and inflammation markers. The goal was to understand how these non-drug products might influence oral and overall health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pHossident lozenge (dietary supplement) and Protektin water additive
- What this could lead to
- If successful, this could show that simple oral hygiene products can positively shift the mouth's microbiome, potentially pointing toward better ways to support oral and whole-body health without drugs.
- What could go wrong
- This is an early-stage observational and exploratory study, not designed to prove any health benefit. The products are supplements, not medicines, so any changes may be small or not clinically meaningful. Results may not apply to everyone.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Comprehensive Research Group
Minneapolis, Minnesota, 55415, United States
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