Brain scans reveal LSD's grip on serotonin receptors
NCT ID NCT05953038
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study uses brain imaging to measure how LSD attaches to serotonin 2A receptors in the brain. Healthy volunteers receive a small dose of LSD, and researchers track how much of the drug reaches these receptors and how it relates to the intensity of the experience. The goal is to better understand the biological basis of LSD's effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LSD (lysergic acid diethylamide)
What this could lead to
If successful, this could help explain how LSD produces its effects on the brain, potentially guiding future research into psychedelic therapies.
What could go wrong
This is an early-phase study with only 40 healthy participants, so results may not apply to broader populations or have direct medical benefits.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Locations
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Neurobiology Research Unit, Rigshospitalet
Copenhagen, 2100, Denmark