Brain scans reveal LSD's grip on serotonin receptors
NCT ID NCT05953038
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study uses brain imaging to measure how LSD attaches to serotonin 2A receptors in the brain. Healthy volunteers receive a small dose of LSD, and researchers track how much of the drug reaches these receptors and how it relates to the intensity of the experience. The goal is to better understand the biological basis of LSD's effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LSD (lysergic acid diethylamide)
- What this could lead to
- If successful, this could help explain how LSD produces its effects on the brain, potentially guiding future research into psychedelic therapies.
- What could go wrong
- This is an early-phase study with only 40 healthy participants, so results may not apply to broader populations or have direct medical benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BASIC SCIENCE are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Neurobiology Research Unit, Rigshospitalet
Copenhagen, 2100, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Radioactive tag reveals Drug's exit route in tiny trial
- Mint lozenge and water additive tested for microbiome impact in 595-Person study
- One hard bike ride could change your balance and brain – study reveals
- Brain study seeks to unlock secrets of hand coordination
- Brain zapping study reveals secrets of body awareness and skill learning
- Brain study could pave way for better rehab after injury