Oral combo therapy trial aims to control aggressive blood cancers
NCT ID NCT05600894
Summary
This study is testing if a two-drug oral combination works better than a single oral drug to control symptoms and reduce cancer cells in patients with certain aggressive blood cancers, including chronic myelomonocytic leukemia (CMML). It is a Phase 2 trial with 132 participants, randomly assigned to receive either the combination or the single drug. The main goal is to see if the combination leads to more patients achieving a complete remission, where cancer signs disappear from the blood and bone marrow.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Einstein Campus
The Bronx, New York, 10461, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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NYP/Weill Cornell Medical Center
New York, New York, 10065, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, 60451, United States
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UC Irvine Health Cancer Center-Newport
Costa Mesa, California, 92627, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, 92612, United States
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UCI Health Laguna Hills
Laguna Hills, California, 92653, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Chicago Medicine-Orland Park
Orland Park, Illinois, 60462, United States
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University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, 45219, United States
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University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, 45069, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
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University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, 66205, United States
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
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VCU Massey Comprehensive Cancer Center
Richmond, Virginia, 23298, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
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