Race for an oral ALS treatment ends early

NCT ID NCT04569084

Terminated Disease control Sponsor: Tanabe Pharma America, Inc. Source: ClinicalTrials.gov ↗

Summary

This study aimed to test if an oral version of the drug edaravone could help slow the progression of ALS over 48 weeks. It involved 384 adults recently diagnosed with ALS who showed a specific rate of decline in their physical abilities. The trial was terminated early, so its final results are not available.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Austin Neuromuscular Center

Austin, Texas, 78756, United States
CHU de Quebec-Hopital-Enfant-Jesus

Québec, Quebec, G1J 1Z4, Canada
Centre Hospitalier De L'Universite De Montreal (Chum) Notre-Dame Hospital

Montreal, Quebec, H2L 4M1, Canada
Centro SLA di Palermo

Palermo, 90129, Italy
Charite Campus Virchow

Berlin, 13353, Germany
Chiba University Hospital

Chiba, 260-8677, Japan
Dent Neurologic Institute

Amherst, New York, 14226, United States
Deutsche Klinik fuer Diagnostik

Wiesbaden, 65191, Germany
Emory University - School of Medicine

Atlanta, Georgia, 30322, United States
Fondazione Serena Onlus - Azienda Ospedaliera Niguarda Ca Granda - Centro Clinico Nemo (Neuro Muscular Omnicentre)

Milan, Italy, Italy
Fukushima Medical University Hospital

Fukushima, Fukushima, 960-1295, Japan
Georg-August-Universitaet Goettingen - Universitaetsmedizin Goettingen (UMG)

Göttingen, 37075, Germany
Hanyang University Medical Center

Seoul, 04763, South Korea
Health Science Center Mcmaster University

Hamilton, Ontario, L8P 1H1, Canada
Hiroshima University Hospital

Minami-ku, Hiroshima-shi, Hiroshima, 734-8551, Japan
HonorHealth Neurology

Scottsdale, Arizona, 85251, United States
Hopitaux Universitaires de Geneve (HUG) (Hopital Cantonal)

Geneva, 1205, Switzerland
Istituto Auxologico Italiano - Istituto Di Ricovero e Cura a Carattere Scientifico - Istituto Scientifico Ospedale San Luca

Modena, 41126, Italy
Istituto Nazionale Neurologico Carlo Besta

Milan, Italy, Italy
Johns Hopkins University

Baltimore, Maryland, 21205, United States
Juntendo University Hospital

Bunkyo-ku, Tokyo, 113-8431, Japan
Kagawa University Hospital

Miki-cho, Kita-gun, Kagawa-ken, 761-0793, Japan
Kansai Electric Power Hospital

Fukushima-ku, Osaka-shi, Osaka, 553-0003, Japan
Keio University Hospital

Shinjuku-ku, Tokyo, 160-8582, Japan
Kitasato University Hospital

Minami-ku, Sagamihara-city, Kanagawa, 252-0375, Japan
Klinikum Rechts der Isar der Technischen Universitaet Muenchen

München, 81675, Germany
Lahey Hospital

Burlington, Massachusetts, 01805, United States
Las Vegas Clinic

Las Vegas, Nevada, 89145, United States
Lewis Katz School of Medicine at Temple University

Philadelphia, Pennsylvania, 19140, United States
Loma Linda University Health Care - Department of Neurology

Loma Linda, California, 92354, United States
London Health Sciences Centre - University Hospital

London, Ontario, N6A 5A5, Canada
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medizinische Hochschule Hannover

Hanover, Lower Saxony, 30625, Germany
Montreal Neurological Institute And Hospital

Montreal, Quebec, H3A 2B4, Canada
Murakami Karindoh Hospital

Nishi-ku, Fukuoka-shi, Fukuoka, 819-8585, Japan
Nagoya University Hospital

Showa-ku, Nagoya, Aichi-ken, 466-8560, Japan
National Hospital Organization Chibahigashi National Hospital

Chuo-ku, Chiba-shi, Chiba, 260-8712, Japan
National Hospital Organization Higashinagoya National Hospital

Meito-ku, Nagoya-shi, Aichi-ken, 465-8620, Japan
National Hospital Organization Hokkaido Medical Center

Sapporo, Hokkaido, 063-0005, Japan
National Hospital Organization Iou National Hospital

Kanazawa, Ishikawa-ken, 920-0192, Japan
National Hospital Organization Kumamoto Saishun Medical Center

Koshi-shi, Kumamoto, 861-1196, Japan
National Hospital Organization Osaka Toneyama Medical Center

Toyonaka-shi, Osaka, 560-8552, Japan
National Hospital Organization Shizuoka Institute of Epilepsy and Neurological Disorders

Aoi-ku, Shizuoka-shi, Shizuoka, 420-8688, Japan
National Hospital Organization Utano National Hospital

Ukyo-ku, Kyoto City, Kyoto, 616-8255, Japan
Nerve And Muscle Center Of Texas

Houston, Texas, 77019, United States
Neurocenter of Southern Switzerland

Lugano, 6903, Switzerland
Neurology Associates, P.C. - Lincoln

Lincoln, Nebraska, 68506-2960, United States
Niigata University Medical & Dental Hospital

Asahimachidori, Chuo-ku, Niigata-shi, Niigata, 951-8520, Japan
Northwestern University Feinberg School of Medicine

Chicago, Illinois, 60611-2605, United States
Ochsner Center for Primary Care and Wellness

Jefferson, Louisiana, 70121, United States
Odette Cancer Center-Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
Ospedale San Raffaele (HSR) (Istituto Scientifico Universitario San Raffaele)

Milan, 20132, Italy
Penn State Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Policlinico A. Gemelli

Roma, CAP 00168, Italy
Recherche Sepmus, Inc

Greenfield Park, Quebec, J4V 2J2, Canada
Regional Health Authority B

Fredericton, New Brunswick, E3B 0C7, Canada
SUNY Upstate Medical University

Syracuse, New York, 13210, United States
Saitama Neuropsychiatric Institute

Chuo-ku, Saitama-shi, Saitama, 338-8577, Japan
Samsung Medical Center

Seoul, 06351, South Korea
Saskatoon City Hospital

Saskatoon, Saskatchewan, S7K 0M7, Canada
Sentara Neurology Specialists

Virginia Beach, Virginia, 23456, United States
Seoul National University Hospital

Seoul, 03080, South Korea
Shiga University of Medical Science Hospital

Ōtsu, Shiga, 520-2192, Japan
St. Joseph's Hospital and Medical Center (SJHMC)

Phoenix, Arizona, 85013, United States
St. Luke's Rehabilitation Institute

Spokane, Washington, 99202, United States
Teikyo University Hospital

Itabashi-ku, Tokyo, 173-8606, Japan
The University of Vermont (UVM) and UVM Medical Center National ALS Center of Excellence

Burlington, Vermont, 05401-3456, United States
Thomas Jefferson University, Jefferson Weinberg ALS Center

Philadelphia, Pennsylvania, 19107, United States
Toho University Omori Medical Center

Ōta-ku, Tokyo, 143-8541, Japan
Tohoku University Hospital

Sendai, Miyagi, 980-8574, Japan
Tokyo Metropolitan Neurological Hospital

Fuchū, Tokyo, 183-0042, Japan
UCSD Medical Center

La Jolla, California, 92037-0897, United States
UF Health Cancer Center

Gainesville, Florida, 32610-3633, United States
UKRUB - Berufsgenossenschaftliches Universitatsklinikum Bergmannsheil GmbH - Medizinische Klinik III

Bochum, North Rhine-Westphalia, 44789, Germany
Universita degli Studi di Torino - Centro Regionale Esperto Per La Sclerosi Laterale Amiotrofica (CRESLA)

Turin, Piedmont, 10126, Italy
Universitaets- und Rehabilitationskliniken Ulm

Ulm, 89081, Germany
Universitaetsklinikum Jena

Jena, 86899, Germany
Universitaetsklinikum Wuerzburg

Wuezburg, Germany, 97080, Germany
University California Los Angeles Medical Center (UCLA)

Los Angeles, California, 90095, United States
University Medical Center Rostock

Rostock, 18147, Germany
University Of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15261, United States
University hospital Bern (Inselspital)

Bern, Canton of Bern, 3010, Switzerland
University of Alberta - Walter C Mackenzie Health Sciences Centre (WCM)

Edmonton, Alberta, T6G 2B7, Canada
University of California Irvine (UCI) Health - Women's Healthcare Center

Orange, California, 92868, United States
University of Colorado Anschutz Medical Campus

Aurora, Colorado, 80045, United States
University of South Florida (USF) - Carol and Frank Morsani Center for Advanced Health Care (CAHC)

Tampa, Florida, 33616, United States
University of Washington Medical Center

Seattle, Washington, 98195, United States
Universitätsklinik Bonn-Motoneuronambulanz, Klinik und Poliklinik für Neurodegenerative Erkrankungen und Gerontopsychiatrie

Bonn, 53127, Germany
Wesley Neurology Clinic, P.C.

Cordova, Tennessee, 38018, United States
West Virginia University School of Medicine (WVUSoM) - Movement Disorder Clinic

Morgantown, West Virginia, 26506-9180, United States
Woodland Research Northwest

Rogers, Arkansas, 72758, United States
Yokohama City University Hospital

Kanazawa-ku, Yokohama-shi, Kanagawa, 236-0004, Japan
Zentrumsleiter Muskelzentrum/ALS Clinic Kantonsspital St.Gallen Muskelzentrum/ALS Clinic

Sankt Gallen, 9107, Switzerland

Conditions

Explore the condition pages connected to this study.

ALS