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ALS drug trial extended to test Long-Term benefits

NCT ID NCT05151471

Terminated Disease control Sponsor: Tanabe Pharma America, Inc. Source: ClinicalTrials.gov ↗

Summary

This study aimed to see if continuing an oral medication called edaravone for up to 48 more weeks could help slow the progression of ALS (amyotrophic lateral sclerosis) in people who had already completed a previous trial. It involved 202 participants and compared two different dosing schedules. The main goal was to measure how long it took for a person's physical abilities to decline significantly or for death to occur.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Quebec-Hopital-Enfant-Jesus

    Québec, Quebec, G1J 1Z4, Canada

  • Chefarzt Muskelzentrum/ALS Clinic Kantonsspital St.Gallen Muskelzentrum/ALS Clinic

    Sankt Gallen, 9007, Switzerland

  • Emory University - School of Medicine

    Atlanta, Georgia, 30317-2819, United States

  • Fukushima Medical University Hospital

    Fukushima, Fukushima, 960-1295, Japan

  • Hanyang University Medical Center

    Wangsimni-ro, Seongdong-gu, 04763, South Korea

  • Health Science Center Mcmaster University

    Hamilton, Ontario, L8P 1H1, Canada

  • Hiroshima University Hospital

    Hiroshima, Hiroshima, 734-8551, Japan

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Kagawa University Hospital

    Kita-gun, Kagawa-ken, 761-0793, Japan

  • Kansai Electric Power Hospital

    Osaka, Osaka, 553-0003, Japan

  • London Health Sciences Centre - University Hospital

    London, Ontario, N6A 5A5, Canada

  • Murakami Karindoh Hospital

    Fukuoka, Fukuoka, 819-8585, Japan

  • Nagoya University Hospital

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Hospital Organization Chibahigashi National Hospital

    Chiba, Chiba, 260-8712, Japan

  • National Hospital Organization Higashinagoya National Hospital

    Nagoya, Aichi-ken, 465-8620, Japan

  • National Hospital Organization Iou National Hospital

    Kanazawa, Ishikawa-ken, 920-0192, Japan

  • National Hospital Organization Kumamoto Saishun Medical Center

    Kōshi, Kumamoto, 861-1196, Japan

  • National Hospital Organization Osaka Toneyama Medical Center

    Toyonaka, Osaka, 560-8552, Japan

  • National Hospital Organization Shizuoka Institute of Epilepsy and Neurological Disorders

    Shizuoka, Shizuoka, 420-8688, Japan

  • National Hospital Organization Utano National Hospital

    Kyoto, Kyoto, 616-8255, Japan

  • Nerve And Muscle Center Of Texas

    Houston, Texas, 77019, United States

  • Neurology Associates, P.C - Lincoln

    Lincoln, Nebraska, 68506, United States

  • Niigata University Medical & Dental Hospital

    Niigata, Niigata, 951-8520, Japan

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611-2605, United States

  • Saitama Neuropsychiatric Institute

    Saitama, 338-8577, Japan

  • Teikyo University Hospital

    Itabashi-ku, Tokyo, 173-8606, Japan

  • Toho University Omori Medical Center

    Ōta-ku, Tokyo, 143-8541, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, 980-8574, Japan

  • Tokyo Metropolitan Neurological Hospital

    Fuchū, Tokyo, 183-0042, Japan

  • UF Health Cancer Center/Clinical Trials Office

    Gainesville, Florida, 32610-3633, United States

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97080, Germany

  • University Of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Alberta - Walter C Mackenzie Health Sciences Centre (WCM)

    Edmonton, Alberta, T6G 2B7, Canada

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

  • West Virginia University School of Medicine (WVUSoM) - Movement Disorder Clinic

    Morgantown, West Virginia, 26506-9180, United States

  • Woodland Research Northwest, LLC

    Rogers, Arkansas, 72758, United States

  • Yokohama City University Hospital

    Yokohama, Kanagawa, 236-0004, Japan

Conditions

Explore the condition pages connected to this study.

ALS