New pill combo offers hope for older leukemia patients who Can't handle chemo
NCT ID NCT07507760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking two oral medications (decitabine and ivosidenib) together can control acute myeloid leukemia (AML) in patients aged 60+ or those too frail for standard chemo. About 50 participants will take the pills in 28-day cycles until the disease worsens or side effects become too severe. The goal is to achieve complete remission, but treatment is lifelong, so this is about disease control, not a cure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Complejo Hospitalario Regional Reina Sofía
Córdoba, 14004, Spain
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Complejo Hospitalario de Albacete
Albacete, 02006, Spain
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Fundación Jiménez Díaz
Madrid, 28040, Spain
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H. 12 de Octubre
Madrid, Spain
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H. Dr. Peset
Valencia, Spain
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Hospital General Universitario Dr. Balmis
Alicante, Spain
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Hospital San Pedro Alcántara
Cáceres, Spain
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Hospital Univeristario Ramón y Cajal
Madrid, Spain
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Hospital Universitari i Politècnic La Fe
Valencia, Spain
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Hospital Universitario Lucus Augusti
Lugo, Spain
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Hospital Universitario Virgen Del Rocío
Seville, Spain
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Hospital Universitario de Burgos
Burgos, 09006, Spain
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Hospital Universitario de Canarias
Las Palmas de Gran Canaria, Spain
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Hospital Universitario de Gran Canaria Doctor Negrín
Las Palmas, Spain
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Hospital Virgen de la Victoria
Málaga, Spain