New pill aims to tame Crohn's bowel inflammation

NCT ID NCT06233461

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new oral medication called TAK-279 can reduce inflammation and ulcers in the bowel for people with moderate to severe Crohn's disease. About 268 adults who haven't gotten enough relief from their current treatments will take one of three doses of TAK-279 or a placebo pill for a year. Doctors will use a camera (endoscopy) to look inside the bowel after 12 weeks to see if the inflammation has improved.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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A. Gemelli University Hospital, Catholic University of the Sacred Heart
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Roma, 00168, Italy

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Aalborg Hospital
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Aalborg, 9100, Denmark

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Accout Center, s.r.o.- Gastroenterologicka ambulancia
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Šahy, 936 01, Slovakia

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Acibadem City Clinic Mladost Hospital
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Sofia, 1784, Bulgaria

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Acibadem City clinic Tokuda hospital
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Sofia, 1407, Bulgaria

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Addenbrooke's Hospital - Cambridge University Hospitals NHS Foundation Trust
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Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom

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Agaplesion Markus Krankenhaus
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Frankfurt am Main, 60431, Germany

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Akershus University Hospital
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Lorenskog, Akershus, 1478, Norway

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AmiCare Sp. z o.o. Sp. k.
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Amsterdam University Medical Center (Amsterdam UMC), Vrije University Medical Center (VUMC)
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Amsterdam, 1081, Netherlands

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Asan Medical Center (AMC)
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Seoul, 05505, South Korea

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Atlanta Center For Gastroenterology, P.C.
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Decatur, Georgia, 30033, United States

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Auzmer Research
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Lakeland, Florida, 33813, United States

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Axon Clinical s.r.o.
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Prague, 15000, Czechia

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Palermo, 90146, Italy

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Azienda Ospedaliera San Camillo Forlanini
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Rome, 00152, Italy

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BVL Clinical Research
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Liberty, Missouri, 64068, United States

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CHU De Clermont Ferrand - Hopital Estaing
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Clermont-Ferrand, 63000, France

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CHU Saint-Pierre - Porte de Hal
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Brussels, 1000, Belgium

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Centre Hospital Regional Et Universitaire De Tours (Chru Tours) - Houpital Trousseau
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Chambray-lès-Tours, 37170, France

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Centre Hospitalier Regional Universitaire de Nancy, Hopital Brabois
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Vandœuvre-lès-Nancy, 54511, France

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Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman
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Liège, 4000, Belgium

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Centre Hospitalier de l'Universite de Montreal
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Montreal, Quebec, H2X 0A9, Canada

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Centrum Badan Klinicznych
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Wroclaw, 51-162, Poland

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Centrum Medyczne Med-Gastr
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Lodz, 91-034, Poland

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Centrum Medyczne Medyk Sp. z o.o. Sp. K.
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Rzeszów, 35-326, Poland

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Centrum Medyczne Melita Medical
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Wroclaw, Lower Silesian Voivodeship, 50-449, Poland

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Changhua Christian Hospital
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Changhua, Changhua County, 50006, Taiwan

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China Medical University (CMU) - Shengjing Hospital (The Second Affiliated Hospital) - Huaxiang Campus
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Shenyang, Liaoning, 110022, China

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China Medical University Hospital
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Taichung, 40447, Taiwan

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Chongqing General Hospital
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Chongqing, Chongqing Sheng, 400013, China

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Clinexpert
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Budapest, 1033, Hungary

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Clinica Medicum
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Bucharest, 012015, Romania

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Clinical Hospital Colentina-Spitalul Clinic Colentina
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Bucharest, 0 50159, Romania

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Cliniq s. r. o.
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Bratislava, 811 09, Slovakia

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Concord Repatriation General Hospital
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Sydney, New South Wales, 2139, Australia

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Diagnostic-Consultative Center Aleksandrovska EOOD
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Sofia, 1431, Bulgaria

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Digestive Disease Institute, Shaare Zedek Medical Center
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Jerusalem, 9103102, Israel

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ETG Zamosc
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Zamość, 22400, Poland

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Emory University Hospital, The Emory Clinic
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Atlanta, Georgia, 30322, United States

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EndoArt
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Ostrava, 71000, Czechia

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Endohope Clinic
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Prague, 10100, Czechia

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Endomed
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Košice, 4013, Slovakia

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Evangelismos Hospital
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Athens, Attica, 106 76, Greece

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Fakultna Nemocnica s poliklinikou Nove Zamky
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Nové Zámky, 94034, Slovakia

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Banská Bystrica, 97401, Slovakia

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Fakultni Nemocnice Ostrava (FNO)
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Ostrava-Poruba, 708 52, Czechia

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Flinders Medical Centre
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Bedford Park, South Australia, 5042, Australia

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Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli e Regina Elena - Clinica Mangiagalli
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Milan, 20122, Italy

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Fraser Clinical Trials
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New Westminster, British Columbia, V3L 3W4, Canada

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Fukuoka University Hospital
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Fukuoka, 814-0180, Japan

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G.N.A. Gennimatas
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Athens, 15669, Greece

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GI PROS, Inc.
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Naples, Florida, 34102, United States

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GastroIntestinal BioSciences
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Los Angeles, California, 90067, United States

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Gastroenterology Associates, PA
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Greenville, South Carolina, 29615, United States

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Gastromed Kopon, Zmudzinski i Wspolnicy Sp.j. Specjalistyczne Centrum Gastrologii i Endoskopii Specjalistyczne Gabinety Lekarskie
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Torun, Kujawsko-pomo, 87-100, Poland

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Gastromedic s.r.o
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Pardubice, 530 03, Czechia

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Great Lakes Gastroenterology Research, LLC
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Mentor, Ohio, 44060, United States

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H-T. Centrum Medyczne Sp. z o.o. Sp.k.
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Tychy, 43-100, Poland

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Hamamatsu University Hospital
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Hamamatsu, Shizuoka, 431-3192, Japan

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Harry Perkins Medical Research Institute Fiona Stanley Hospital
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Murdoch, Western Australia, 6150, Australia

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Hepato-Gastroenterologie HK, s.r.o.
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Hradec Králové, 50012, Czechia

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Heritage Medical Research Clinic - University Of Calgary
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Calgary, Alberta, T2N 4Z6, Canada

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Hillerod Hospital, Hilleroed Sygehus
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Hillerød, 3400, Denmark

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Hopital Nord Chu Saint-Etienne
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Saint-Etienne, 42055, France

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Hopital Universitaire de Bruxelles/ Academisch Ziekenhuis Brussel
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Brussels, Anderlecht / Region Capitale de Bruxelles/ Brussel, 1070, Belgium

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Hopital l'Archet 2
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Nice, 06202, France

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Hvidovre Hospital Medicinsk Gastroenterologisk Afdeling
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Hvidovre, 2650, Denmark

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Hyogo Medical University Hospital
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Nishinomiya, Hyōgo, 663-8501, Japan

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IRCCS - AOU di Bologna - SantOrsola Malpighi
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Bologna, 40138, Italy

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IRCCS Istituto clinico humanitas - Humanitas Mirasole spa
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Rozzano, 20089, Italy

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Icahn School of Medicine at Mount Sinai (ISMMS) - The Mount Sinai Hospital (MSH)
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New York, New York, 10029, United States

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Inje University Haeundae Paik Hospital
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Busan, 48108, South Korea

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Institute of Science Tokyo Hospital
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Tokyo, 113-8519, Japan

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Institutul Clinic Fundeni
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Bucharest, 022328, Romania

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Intesto - Gastroenterologische Praxis & Crohn-Colitis-Zentrum Bern
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Bern, 3012, Switzerland

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Iwate Medical University Uchimaru Medical Center
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Morioka, Iwate, 020-8505, Japan

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Kansai Medical University Hospital
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Hirakata, Osaka, 5731191, Japan

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Keimyung University Dongsan Hospital
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Daegu, 42601, South Korea

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Korczowski Bartosz, Gabinet Lekarski
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Rzeszów, 35302, Poland

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Kosin University Gospel Hospital
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Busan, 49267, South Korea

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Kyorin University Hospital
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Mitaka, Tokyo, 181-8611, Japan

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Las Vegas Medical Research
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Las Vegas, Nevada, 89128, United States

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London Health Sciences Centre - University Hospital
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London, Ontario, N6A 5A5, Canada

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London Health Sciences Centre - Victoria Hospital
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London, Ontario, N6A 5W9, Canada

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Manermed Sp. z o.o - CM Medis
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Bydgoszcz, 85229, Poland

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Masaryk Hospital
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Ústí nad Labem, 40113, Czechia

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Mater Cancer Care Centre-Mater Health Services
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South Brisbane, Queensland, 4101, Australia

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Medrise sp. z o.o
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Lublin, 20-582, Poland

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Meir Medical Center
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Kfar Saba, 44281, Israel

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Mohacsi Korhaz
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Mohács, 7700, Hungary

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Multi-Profile Hospital for Active Treatment (MHAT) Hadji Dimitar
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Sliven, 8800, Bulgaria

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NH Hospital
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Hořovice, Central Bohemia, 268 31, Czechia

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National Taiwan University Hospital
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Taipei, Zhongzheng District, 100, Taiwan

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Nemocnice Ceske Budejovice, a.s.
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České Budějovice, 370 01, Czechia

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Northern Hospital Epping
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Epping, 3076, Australia

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Nova Scotia Health Authority - Queen Elizabeth II Heath Sciences Centre
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Halifax, Nova Scotia, B3H 2Y9, Canada

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Novel Research, LLC
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Bellaire, Texas, 77401, United States

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Oddzial Kliniczny Gastroenterologii Ogolnej i Onkologicznej SPZOZ Uniwersytecki Szpital Kliniczny Nr 1 im. Barlickiego Uniwersytetu Medycznego w Lodzi
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Lodz, 90-153, Poland

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Odense Universitetshospital (OUH) (Odense University Hospital)
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Odense, Region Syddanmark, 5000, Denmark

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Osaka Medical College Hospital
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Takatsuki-shi, Osaka, 569-8686, Japan

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Oslo Univeristy Hospital Ulleval Hospital
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Oslo, 0450, Norway

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Ospedale San Raffaele (HSR) Instituto Scientifico Universitario San Raffaele
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Milan, 20132, Italy

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Pannonia Maganorvosi Centrum Kft.
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Budapest, 1136, Hungary

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Panstwowy Instytut Medyczny MSWiA
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Warsaw, Masovian Voivodeship, 02-507, Poland

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PlanetMed Sp. z o.o.
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Wroclaw, Lower Silesian Voivodeship, 52-210, Poland

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Policlinica Algomed: Centrul De Gastroenterologie Dr. Goldis
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Timișoara, Jud Timis, 300002, Romania

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Region Sjaelland Sygehus Nord, Koge Sygehus
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Køge, 4600, Denmark

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Renji Hospital Shanghai Jiao Tong University School of Medicine
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Shanghai, Shanghai Municipality, 200127, China

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Rochester Clinical Research
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Rochester, New York, 14609, United States

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Royal Perth Hospital
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Perth, Western Australia, 6000, Australia

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Samsung Medical Center
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Seoul, 06351, South Korea

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Sapporo Medical University Hospital
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Sapporo, Hokkaido, 060-8543, Japan

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Semmelweis Egyetem
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Budapest, 1082, Hungary

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Severance Hospital, Yonsei University Health System
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Seoul, 03722, South Korea

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Shanghai Pudong New District Zhoupu Hospital
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Shanghai, 201318, China

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Sir Charles Gairdner Hospital (SCGH) - Comprehensive Cancer Centre
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Nedlands, 6009, Australia

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Soroka Mc
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Beersheba, 84101, Israel

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Sotiria General Hospital of Athens
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Athens, 11527, Greece

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South Eastern Health and Social Care Trust - The Ulster Hospital
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Belfast, BT16 1RH, United Kingdom

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Southern Star Research Institute, LLC
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San Antonio, Texas, 78229, United States

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Spital Clinic Dr I Cantacuzino
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Bucharest, 020475, Romania

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Spitalul Euroclinic
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Bucharest, 14461, Romania

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St Thomas' Hospital - Guy's & St Thomas' NHS Foundation Trust
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London, SE1 7EH, United Kingdom

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St. Elisabeth Ziekenhuis
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Tilburg, 5022 GC, Netherlands

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St. Marien- und St. Annastiftskrankenhaus
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Ludwigshafen, 67065, Germany

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Sun Yat-sen University (SYSU) - The First Affiliated Hospital
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Guangzhou, Guangdong, 510080, China

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Sun Yat-sen University - The Sixth Affiliated Hospital (Guangdong Gastrointestinal Hospital)
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Guangzhou, 510655, China

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SurGal Clinic SRO
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Brno, 602 00, Czechia

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Sydvestjysk Region/Esbjerg Hospital
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Esbjerg, 6700, Denmark

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TDDC dba Alliance Research
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Mansfield, Texas, 76063, United States

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Texas Digestive Disease Consultants, PLLC d/b/a GI Alliance
RECRUITING

Fort Worth, Texas, 76104, United States

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The Chaim Sheba Medical Center - The Edmond and Lily Safra Children's Hospital
RECRUITING

Ramat Gan, 5265601, Israel

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The Chaim Sheba Medical Centre
RECRUITING

Tel Aviv, 5265601, Israel

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The Jikei University Hospital
RECRUITING

Minato, Tokyo, 105-8471, Japan

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The Queen Elizabeth Hospital
RECRUITING

Woodville, South Australia, 5011, Australia

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The Research Institute of the McGill University Health Center
RECRUITING

Montreal, Quebec, H3G 1A4, Canada

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The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310009, China

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The Second Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410011, China

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The University of Iowa Hospitals & Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

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Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan

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Toyama University Hospital
RECRUITING

Toyama, 930-0194, Japan

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Tsujinaka Hospital Kashiwanoha
RECRUITING

Chiba, 277-0871, Japan

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Twoja Przychodnia - Szczecinskie Centrum Medyczne
RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-434, Poland

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Tyler Research Institute, LLC
RECRUITING

Tyler, Texas, 75701, United States

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UCI Health
RECRUITING

Orange, California, 92868, United States

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UMBAL Kaspela
RECRUITING

Plovdiv, 4001, Bulgaria

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USF Health Morsani Center for Advanced Healthcare
RECRUITING

Tampa, Florida, 33612, United States

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United Medical Doctors
RECRUITING

Murrieta, California, 92563, United States

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Universitaetsklinik Frankfurt
RECRUITING

Frankfurt, 60590, Germany

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Universitaetsklinikum Mannheim GmbH
RECRUITING

Mannheim, 68167, Germany

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Universitaetsklinikum Schleswig-Holstein, UKSH-Campus Kiel
RECRUITING

Kiel, 24105, Germany

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Universitaetsklinikum Tuebingen
RECRUITING

Tübingen, 72076, Germany

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Universitair Ziekenhuis Leuven
RECRUITING

Leuven, 3000, Belgium

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University Gastroenterology Providence
RECRUITING

Providence, Rhode Island, 02904, United States

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University General Hospital of Patras
RECRUITING

Pátrai, Achaia, 26504, Greece

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University Hospital Basel
RECRUITING

Basel, 4031, Switzerland

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University Hospital Brno
NOT_YET_RECRUITING

Brno, 639 00, Czechia

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University Hospital Of Ulm, Universitatsklinikum Ulm
RECRUITING

Ulm, 89081, Germany

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University Hospital Tsaritsa Yoanna - Isul (University Hospital Queen Giovanna)
RECRUITING

Sofia, 1527, Bulgaria

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University Hospital of Heraklion
RECRUITING

Heraklion, Crete, 71110, Greece

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University Of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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University of Athens School of Medicine, Alexandra General Hospital
RECRUITING

Athens, Attica, 11528, Greece

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University of Toronto - Mount Sinai Hospital - The Lunenfeld-Tanenbaum Research Institute
RECRUITING

Toronto, Ontario, M5G 1X5, Canada

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University of Washington Medical Center
RECRUITING

Seattle, Washington, 98195, United States

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Vojenska Nemocnice Brno
RECRUITING

Brno, 636 00, Czechia

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WIP Warsaw IBD Point Profesor Kierkus
RECRUITING

Warsaw, 04-501, Poland

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Wellness Clinical Research
RECRUITING

Miami Lakes, Florida, 33016, United States

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West Central Gastroenterology, LLP, d/b/a/ Gastro Florida
RECRUITING

Clearwater, Florida, 33762, United States

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Western Health/Footscray Hospital
RECRUITING

Melbourne, Victoria, 3011, Australia

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Wingate Institute for Neurogastroenterology, Wingate Clinical Trials Facility, Barts Health NHS Trust
RECRUITING

London, E1 2at, E1 2AT, United Kingdom

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Woodholme Gastroenterology Associates
RECRUITING

Glen Burnie, Maryland, 21061, United States

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Yonsei University Wonju Severance Christian Hospital
RECRUITING

Wŏnju, Gangwon-do, 26426, South Korea

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Zhejiang University School of Medicine - Sir Run Run Shaw Hospital (SRRSH)
RECRUITING

Hangzhou, 310016, China

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Zhongshan Hospital Xiamen University
RECRUITING

Xiamen, Fujian, 361000, China

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Zuyderland Medisch Centrum - Sittard-Geleen
RECRUITING

Geleen, Limburg, 6162 BG, Netherlands

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Conditions

Explore the condition pages connected to this study.

CROHN'S DISEASE