Could less radiation be just as effective for some head and neck cancers?

NCT ID NCT05145660

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving radiation only to the involved lymph nodes (instead of the whole neck area) can control early-stage nasopharyngeal cancer just as well, with fewer side effects. About 414 adults with limited lymph node involvement will be randomly assigned to either standard or smaller radiation fields. The goal is to see if the smaller approach maintains cancer control while improving quality of life.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)

    Beijing, 100021, China

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