Could less chemo be better for brain lymphoma? major trial seeks answers

NCT ID NCT04931368

First seen Apr 01, 2026 · Last updated May 13, 2026 · Updated 10 times

Summary

This study tests whether a reduced-intensity chemotherapy regimen works better than the standard treatment for people newly diagnosed with primary CNS lymphoma, a rare brain cancer. About 331 adults aged 18 to 70 will receive either the standard MATRix protocol or a milder version. The goal is to see if the gentler approach improves how long patients stay free of major events like progression or severe side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Klinikum Stuttgart

    Stuttgart, Baden-Wurttemberg, 70174, Germany

Conditions

Explore the condition pages connected to this study.