Lung cancer biopsy study: fewer needle passes may be enough for genetic tests
NCT ID NCT05560776
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at the best way to collect tissue samples from lung cancer patients using a thin tube passed through the mouth (endobronchial ultrasound). It compares taking 2 versus 3 samples from each lymph node to see if fewer samples still provide enough material for genetic testing. It also checks if a simple blood test (liquid biopsy) can find genetic changes that the tissue sample might miss. The goal is to make testing easier and more complete for people with suspected non-small cell lung cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Endobronchial ultrasound (EBUS) procedure with 2 or 3 needle passes per lymph node, plus liquid biopsy (blood test)
What this could lead to
If successful, this could help doctors get enough tissue for genetic testing with fewer needle passes, and show that a blood test can find important genetic changes missed by tissue biopsy.
What could go wrong
This is a small, early-stage study (120 people) at one hospital, so results may not apply to everyone. It tests a procedure, not a new drug, so it won't directly treat lung cancer.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Institut Universitaire de Cardiologie et Pneumologie de Quebec
Québec, Quebec, G1V4G5, Canada