New balloon could open blocked ureters without surgery
NCT ID NCT07020520
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a special balloon coated with the drug paclitaxel to treat narrowed sections of the ureter (the tube from kidney to bladder). The balloon is inflated to widen the stricture and release the drug to help keep it open. Researchers will check if the treatment is safe and successful in 60 adults over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- paclitaxel-coated balloon (Optilume)
- What this could lead to
- If successful, this could offer a less invasive treatment option for ureter strictures, potentially avoiding repeated surgeries.
- What could go wrong
- This is an early feasibility study with only 60 people, so results may not apply to everyone. Risks include sensitivity to paclitaxel or the stricture returning.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
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Mount Sinai
RECRUITINGNew York, New York, 10003, United States
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NYU Langone
RECRUITINGNew York, New York, 10016, United States
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Orlando Health
RECRUITINGOrlando, Florida, 32806, United States
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University of California Irvine
RECRUITINGOrange, California, 92868, United States
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University of Texas Southwestern
RECRUITINGDallas, Texas, 75390, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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