Blood level monitoring could speed sepsis recovery

NCT ID NCT07270523

Not yet recruiting Disease control Sponsor: Complexo Hospitalario Universitario de A Coruña Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adjusting beta-lactam antibiotics based on blood levels helps critically ill sepsis patients recover faster. 198 adults in the ICU will be randomly assigned to either standard dosing or dosing guided by regular blood tests. The goal is to see if personalized dosing reduces time to full clinical recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: beta-lactam antibiotics
What this could lead to: If successful, this could show that personalized antibiotic dosing helps sepsis patients recover faster and reduces hospital stays.
What could go wrong: This is a single-center trial with 198 patients, so results may not apply broadly. The intervention is monitoring, not a new drug, so the impact may be modest.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL SEPSIS

Contacts and locations

Locations

Clinical Hospital of Santiago de Compostela

Santiago de Compostela, A Coruña, 15705, Spain

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